ETF comparison
IBB vs VHT
Both Healthcare.
iShares Biotechnology ETF · Vanguard Health Care Index Fund ETF Shares
Holdings overlap
181 positions appear in both funds. Buying equal dollars of IBB and VHT would leave roughly 18.9% of each dollar exposed to the same underlying securities.
Unmatched is the part of a fund's weight the other fund doesn't match: names only it holds, plus any extra weight it puts in names both funds hold.
Side by side
Sub-score comparison
Tracking quality isn't part of the composite — see what we don't score for why.
Cost difference
VHT is 35 bps cheaper than IBB. On a $100,000 position that's about $350/yr more in fees for IBB.
Fee figure is the annual expense charged on $100,000. To see how the gap compounds over a multi-decade holding period, open the cost calculator pre-filled with IBB vs VHT.
Top shared holdings
181 shared in total| # | Holding | In IBB | In VHT | Overlap |
|---|---|---|---|---|
| 1 | Amgen, Inc. | 7.83% | 3.21% | 3.21% |
| 2 | Gilead Sciences, Inc. | 6.84% | 2.52% | 2.52% |
| 3 | Vertex Pharmaceuticals, Inc. | 8.08% | 1.92% | 1.92% |
| 4 | Regeneron Pharmaceuticals, Inc. | 4.91% | 1.15% | 1.15% |
| 5 | Natera, Inc. | 2.89% | 0.60% | 0.60% |
| 6 | Moderna, Inc. | 1.98% | 0.56% | 0.56% |
| 7 | Revolution Medicines, Inc. | 2.78% | 0.46% | 0.46% |
| 8 | Alnylam Pharmaceuticals, Inc. | 3.12% | 0.44% | 0.44% |
| 9 | Illumina, Inc. | 2.07% | 0.44% | 0.44% |
| 10 | Biogen, Inc. | 2.47% | 0.44% | 0.44% |
| 11 | Insmed, Inc. | 1.78% | 0.36% | 0.36% |
| 12 | Incyte Corp. | 1.75% | 0.29% | 0.29% |
Only in IBB
67 total- Argenx SE 3.76%
- BeOne Medicines Ltd. 1.77%
- Ascendis Pharma A/S 1.29%
- Genmab A/S 1.12%
- Abivax SA 0.67%
- BioNTech SE 0.66%
- Nuvalent, Inc. 0.50%
- Xenon Pharmaceuticals, Inc. 0.43%
- CRISPR Therapeutics AG 0.38%
- Legend Biotech Corp. 0.33%
Only in VHT
232 total- Eli Lilly & Co 12.87%
- Johnson & Johnson 8.75%
- AbbVie Inc 6.28%
- Merck & Co Inc 5.06%
- UnitedHealth Group Inc 4.90%
- Thermo Fisher Scientific Inc 3.18%
- Abbott Laboratories 2.66%
- Pfizer Inc 2.24%
- Bristol-Myers Squibb Co 1.89%
- Danaher Corp 1.88%
Related comparisons
More comparisons with IBB
- IBB vs FHLC · Fidelity MSCI Health Care Index ETF 17.6%
- IBB vs XLV · State Street Health Care Select Sector SPDR ETF 11.1%
- IBB vs IXJ · iShares Global Healthcare ETF 8.3%
- IBB vs IHF · iShares U.S. Healthcare Providers ETF 0.1%
- IBB vs IHI · iShares U.S. Medical Devices ETF 0.1%
- IBB vs VGT · Vanguard Information Technology Index Fund ETF Shares 0.0%
More comparisons with VHT
- VHT vs IHF · iShares U.S. Healthcare Providers ETF 14.6%
- VHT vs IHI · iShares U.S. Medical Devices ETF 14.2%
- VHT vs XBI · State Street SPDR S&P Biotech ETF 13.3%
- VHT vs VGT · Vanguard Information Technology Index Fund ETF Shares 0.0%
- VHT vs XLK · State Street Technology Select Sector SPDR ETF 0.0%
- VHT vs FHLC · Fidelity MSCI Health Care Index ETF 96.5%
Percentages are holdings overlap with the named fund.
Open IBB or VHT at a brokerage
Both funds trade commission-free at major US brokerages.
Affiliate links — opening an account through these earns PlainIndex a one-time referral. Scoring is computed before any affiliate consideration; see our methodology and funding disclosure.
Holdings overlap is the sum of min(weight_a, weight_b) over positions
matched on ISIN (CUSIP fallback). Methodology: see
/methodology/.
Comparing two funds doesn't endorse swapping one for the other. Tax-lot history, account type, and personal goals matter — PlainIndex publishes data and methodology, not investment advice.